什么是 Exosomes ？
Exosomes derived from mesenchymal stem cells can induce benefit in almost all stages of healing, including control of immune responses, reducing inflammation, promoting cell proliferation and angiogenesis (the formation of new blood vessels).
来自间充质干细胞的外泌体几乎可以在愈合的所有阶段产生益处，包括控制免疫反应、减少炎症、促进细胞增殖和血管生成（新血管的形成）。
Exosomes are powerful elements that can heal and restore cells throughout your body. They enhance cell-to- cell communication, which is essential for overall cell health.
外泌体是强大的元素，可以治愈和恢复整个身体的细胞。 它们增强了细胞间的交流，这对整体细胞健康至关重要。
什么是外泌体疗法 ？
Exosome therapy is a minimally invasive procedure commonly used in orthopedic injuries, for anti- aging and some other degenerative diseases.
外泌体疗法是一种微创医疗，常用于骨科损伤、抗衰老和其他一些退行性疾病。
Exosome therapy is a highly targeted, flexible treatment for conditions like osteoarthritis, chronic pain, and musculoskeletal injuries. Genetic disorders, chronic and degenerative diseases, and the natural aging process can all inhibit your cells’ ability to communicate. Exosome therapy improves the communication channels between cells to stimulate healing.
外泌体疗法是一种针对骨关节炎、慢性疼痛和肌肉骨骼损伤等疾病的高度靶向、灵活的治疗方法。 遗传疾病、慢性和退行性疾病以及自然衰老过程都会抑制细胞的交流能力。 外泌体疗法改善了细胞之间的沟通渠道以刺激愈合。
外泌体疗法如何运作？
Exosomes are responsible, among other things, for assisting both the T-cells and NK cells in our immune system. T-cells are responsible for calming an immune response, while NK cells are responsible for ramping up that response.
除其他外，外泌体负责协助我们免疫系统中的 T 细胞和 NK 细胞。 T 细胞负责平息免疫反应，而 NK 细胞负责加强该反应。
We need both, but when NK cells aren’t “turned off” or T-cells aren’t “turned on,” pain and inflammation are often the result.
我们两者都需要，但是当 NK 细胞没有“关闭”或 T 细胞没有“打开”时，通常会导致疼痛和炎症。
When exosomes are delivered directly into an affected joint, they start signaling to the cells to return to healthy function.
当外泌体直接输送到受影响的关节时，它们开始向细胞发出信号以恢复健康功能。
They send proteins into the walls of the cells telling the cells how to regulate themselves.
它们将蛋白质送入细胞壁，告诉细胞如何自我调节。
There are two stages to the body’s response. In the first stage, which happens almost immediately, the inflammatory response is turned off. In the second stage, the exosomes basically tell the cells how to regulate themselves correctly in the future, leading to long-term relief.
身体的反应有两个阶段。 在几乎立即发生的第一阶段，炎症反应被关闭。 在第二阶段，外泌体基本上告诉细胞未来如何正确调节自身，从而导致长期缓解。
如何管理外泌体？
Exosomes can be injected directly into the affected area such as a joint or intravenously (IV). Dose and treatment frequency depend on the condition being treated.
外泌体可以直接注射到受影响的区域，例如关节或静脉内 (IV)。 剂量和治疗频率取决于所治疗的病症。
The procedure is done in our office on an outpatient basis at FDA. There is virtually no downtime.
该程序是在我们的医学中心在 FDA授权研究使用授权下在洛杉矶和夏威夷檀香山的医学中心门诊完成的。治疗方案均经本会诊中心医学科学专家咨询会诊后量身定制。
外泌体与干细胞？
We now know that the old working hypothesis for how stem cells exert their regenerative effects was wrong. The transplanted stem cells don’t stick around long in the recipient’s body to replace damaged cells; most are cleared within a week.
我们现在知道，关于干细胞如何发挥其再生作用的旧工作假设是错误的。 移植的干细胞不会长时间留在受体体内以替换受损细胞； 大多数在一周内被清除。
The FDA warns of the potential dangers of unproven stem cell therapies, including administration site reactions, the failure of cells to work as expected and the possibility that cells may move from placement sites and change into inappropriate cell types or multiply.
FDA 警告未经证实的干细胞疗法的潜在危险，包括给药部位反应、细胞无法按预期工作以及细胞可能从放置部位移动并变成不适当的细胞类型或繁殖的可能性。
As researchers have now concluded, it’s the exosomes stem cells release, rather than the cells themselves, that impart the regenerative benefit.
正如研究人员现在得出的结论，赋予再生益处的是外泌体干细胞释放，而不是细胞本身。
Exosome therapy would avoid all the problems of a therapy based on live stem cells and yet harness a natural regenerative capability from stem cells.
外泌体疗法将避免基于活干细胞的疗法的所有问题，同时利用干细胞的自然再生能力。
干细胞与外泌体？
Exosome therapy would avoid all the problems of a therapy based on live stem cells and yet harness a natural regenerative capability from stem cells.
外泌体疗法将避免基于活干细胞的疗法的所有问题，同时利用干细胞的自然再生能力。
Unlike stem cells, exosomes can’t replicate or transform into malignant or harmful cells because they themselves aren’t cells. They also can’t be infected with viruses and are less likely to trigger an immunogenic response.
与干细胞不同，外泌体不能复制或转化为恶性或有害细胞，因为它们本身不是细胞。 它们也不会感染病毒，也不太可能引发免疫原性反应。
Their small size gives exosomes the advantage of being able to circulate more easily through the body.
它们的小尺寸使外泌体具有能够更容易地在体内循环的优势。
As a further demonstration of their safety, blood plasma contains high concentrations of unmatched exosomes, and blood transfusions have been carried out in hospitals for decades.
作为其安全性的进一步证明，血浆中含有高浓度的无与伦比的外泌体，数十年来医院一直在进行输血。
外泌体与 PRP（富血小板血浆）？
Exosome is very similar to PRP therapy. It uses the same concept of using growth factors that PRP uses.
外泌体与 PRP 疗法非常相似。 它使用与 PRP 使用的生长因子相同的概念。
Once platelets are in the area that’s being treated with PRP, they break down and release growth factors, which are compounds that help cells repair and renew. This is thought to trigger your body’s healing process
一旦血小板进入使用 PRP 治疗的区域，它们就会分解并释放生长因子，这些生长因子是帮助细胞修复和更新的化合物。 这被认为会触发你身体的愈合过程
The biggest difference with exosome therapy is that these growth factors are not derived from a patient’s own blood.
与外泌体疗法最大的不同是这些生长因素并非来自患者自己的血液。
They are lab derived from donated cord blood with the regenerative capabilities of a newborn.
它们是实验室从捐赠的脐带血中提取的，具有新生儿的再生能力。
Is This a Safe Treatment?
这是一种安全的治疗方法吗？
Your body makes and uses exosomes and knows what to do with them. No long-term negative side effects have ever been reported with this treatment.
你的身体制造和使用外泌体，并且知道如何处理它们。 从未报告过这种治疗的长期负面副作用。
Where Do Exosomes Come From? 外泌体从何而来？
Exosomes are taken from MSC or Mesenchymal stem cells. These stem cells are unique in the human body in that they have the power to differentiate. While all other cells divide and replicate, producing a new cell of precisely the same kind as the original, MSC cells are able to become any type of cell at all.
外泌体取自 MSC 或间充质干细胞。 这些干细胞在人体中是独一无二的，因为它们具有分化的能力。当所有其他细胞分裂和复制产生一个与原始细胞完全相同的新细胞时，MSC 细胞完全能够成为任何类型的细胞。
How Many Treatments Are Necessary?
需要多少次治疗？
Treatment is as unique as every individual who comes through our doors. For some, just one treatment is effective. Others may need multiple treatments depending on the condition or multiple conditions that are being treated.
治疗与每一个进门的人一样独特。 对于一些人来说，只有一种治疗是有效的。 其他人可能需要多次治疗，具体取决于正在治疗的状况或多种状况。
How Long Does It Take to See Results?
需要多长时间才能看到结果？
Results will typically depend factors such as severity of the condition, and how long the condition has persisted. As we age, our bodies become slower to respond to stem cell signals,but don’t be discouraged if results aren’t immediate. It takes the body time to repair itself.It may take three to four months to see results and peak benefit at around nine months post treatment.
结果通常取决于诸如病情严重程度以及病情持续多长时间等因素。 随着年龄的增长，我们的身体对干细胞信号的反应变得更慢，但如果结果不是立竿见影，也不要气馁。 身体需要时间进行自我修复。在治疗后大约 9 个月左右，可能需要三到四个月才能看到结果和最大益处。
Exosomes外泌体纳米干细胞及功能抗衰和慢病精准治疗
VJMMG的医学科学家获Dynacord授权，使用美国FDA唯一临床3期批准可供人类使用的MSC衍生的Exosomes脐带血外泌体间充质干细胞药。Dynacord Exosomes受美国FDA严管不含胎儿组织和克隆，每立方厘米224亿的超高浓度具有诱导对各种医疗问题的再生作用。Dynacord Exosomes还负责协助免疫T细胞和NK细胞的自我调节，抑制炎症和氧化过激反应，再生修复受损组织，常用于免疫调节增强、遗传和退行性疾病及自然衰老过程中对细胞交流的抑制，是迄今全球范围内首屈一指的万能脐带血间充质外泌体干细胞药。
VJMMG experts are authorized by Dynacord to use FDA-approved Phase III MSC-derived exosome stem cell drugs from umbilical cord blood. Dynacord Exosomes, under strict FDA regulation, contain no fetal tissues or cloned materials. With a concentration of 22.4 billion particles per cubic centimeter, they promote regeneration for various medical issues. These exosomes assist immune T-cells and NK-cells in self-regulation, suppress inflammation, repair tissue, and enhance Immune activity. Clinically, they are used for immune modulation, hereditary diseases, degenerative conditions, and aging-related cellular decline, making them a leading global stem cell therapy.
癌症基因检测和再生生物细胞的癌症免疫治疗
RBC Cancer Immunotherapy 再生生物细胞癌症免疫治疗是美国癌症协会定义的免疫疗法，是利用人体免疫系统对抗癌症的治疗方法。是根据人体癌细胞或突变细胞量身定制的抗体的免疫细胞疗法。经体外培养使其靶向识别和杀伤功能增强，其定制的T细胞或NK+DC的抗肿瘤活性更增强了它们破坏癌细胞的能力并提供持久的抗癌抗突变作用，回输到人体来识别和追踪歼灭癌细胞。VJMMG的医学科学专家在人间天堂夏威夷开展Car-T/Car-NK+DC Therapy疗程3-12周不等，并同时提供PNC27肽蛋白基因药和营养支撑的IV Therapy。
Regenerative Bio Cell Cancer Immunotherapy, defined by the American Cancer Society, uses the body’s immune system to fight cancer. This therapy customizes immune cells based on the patient’s antibody of the cancer or mutated cells, enhancing their ability to target and destroy cancer cells through ex vivo cultivation. Modified T-cells or NK+DC cells with stronger anti-tumor activity are reinfused to eliminate cancer cells and provide lasting anti-cancer effects. VJMMG offers Car-T/Car-NK+DC Therapy in Hawaii, with programs lasting 3 to 12 weeks. The treatment includes PNC 27 peptide protein gene medicine and IV nutritional support for comprehensive care
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